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The Brown Fat Switch: Scientists Discover a Molecular Key to Burning Calories and Building Stronger Bones

By Nina Castellani · 1 January 1970 · null min read

References

  • Mohammed Faiz Hussain, Lawrence Kazak et al.. "Glycerol-driven TNAP activation in thermogenesis and mineralization." Nature, 2026-04-22 https://www.nature.com/articles/s41586-026-10396-9
  • Y. Sun, L. Kazak et al.. "Mitochondrial TNAP controls thermogenesis by hydrolysis of phosphocreatine." Nature, 2021-05-12 https://www.nature.com/articles/s41586-021-03533-z
  • Jakub Bunk, Lawrence Kazak et al.. "The Futile Creatine Cycle powers UCP1-independent thermogenesis in classical BAT." Nature Communications, 2025-04-04 https://www.nature.com/articles/s41467-025-58294-4
  • J.-L. Millan, M. D. McKee et al.. "Tissue-nonspecific alkaline phosphatase in mineralized tissue metabolism." Nature Communications, 2021-09-22 https://www.nature.com/articles/s41467-021-25958-w

Nina Castellani

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